Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction-Reference-Cited by-同舟云学术

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Published:2006-05-13 Issue:12 Volume:49 Page:3432-3435
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ding Ke¹,Lu Yipin¹,Nikolovska-Coleska Zaneta¹,Wang Guoping¹,Qiu Su¹,Shangary Sanjeev¹,Gao Wei¹,Qin Dongguang¹,Stuckey Jeanne¹,Krajewski Krzysztof¹,Roller Peter P.¹,Wang Shaomeng¹

Affiliation:

1. Comprehensive Cancer Center and Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, and Life Sciences Institute, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48109, and Laboratory of Medicinal Chemistry, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051122a

Reference19 articles.

1. p53, the Cellular Gatekeeper for Growth and Division

2. Surfing the p53 network

3. Live or let die: the cell's response to p53

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