Synthesis, crystal structure, Hirshfeld surface, computational and biological studies of spiro-oxindole derivatives as MDM2-p53 inhibitors
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Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s11030-024-10974-x.pdf
Reference74 articles.
1. Arun Y, Saranraj K, Balachandran C, Perumal PT (2014) Novel spirooxindole-pyrrolidine compounds: synthesis, anticancer and molecular docking studies. Eur J Med Chem 74:50–64. https://doi.org/10.1016/j.ejmech.2013.12.027
2. Wang Y, Kong H, Zeng X et al (2016) Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells. Oncol Rep 35(4):2053–2064. https://doi.org/10.3892/or.2016.4569
3. Gupta A, Behl T, Heer HR, Deshmukh R, Sharma PL (2019) Mdm2-P53 interaction inhibitor with cisplatin enhances apoptosis in colon and prostate cancer cells in vitro. Asian Pac J Cancer Prev 20:3341–3351. https://doi.org/10.31557/APJCP.2019.20.11.3341
4. Shangary S, Wang S (2008) Targeting the MDM2-p53 interaction for cancer therapy. Clin Cancer Res 14:5318–5324. https://doi.org/10.1158/1078-0432.CCR-07-5136
5. Ding K, Lu Y, Nikolovska-Coleska Z, Wang G et al (2006) Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2—p53 interaction. J Med Chem 2:3432–3435. https://doi.org/10.1021/jm051122a
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