Ru(<scp>ii</scp>)/Os(<scp>ii</scp>)-based carbonic anhydrase inhibitors as photodynamic therapy photosensitizers for the treatment of hypoxic tumours-Reference-Cited by-同舟云学术

Ru(ii)/Os(ii)-based carbonic anhydrase inhibitors as photodynamic therapy photosensitizers for the treatment of hypoxic tumours

Published:2023 Issue:42 Volume:14 Page:11749-11760
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wang Youchao¹,Mesdom Pierre¹,Purkait Kallol¹,Saubaméa Bruno²,Burckel Pierre³,Arnoux Philippe⁴,Frochot Céline⁴^ORCID,Cariou Kevin¹^ORCID,Rossel Thibaud⁵^ORCID,Gasser Gilles¹^ORCID

Affiliation:

1. Chimie ParisTech, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, PSL University, 75005, Paris, France

2. Cellular and Molecular Imaging Facility, US25 Inserm, UAR3612 CNRS, Faculté de Pharmacie de Paris, Université Paris Cité, F-75006, Paris, France

3. Institut de Physique du Globe de Paris, Biogéochimie à; l’Anthropocène des Eléments et Contaminants Emergents, 75005, Paris, France

4. Université de Lorraine, CNRS, LRGP, F-54000, Nancy, France

5. Institute of Chemistry, University of Neuchâtel, Avenue de Bellevaux 51, 2000, Neuchâtel, Switzerland

Abstract

Novel sulfonamide-based monopodal and dipodal ruthenium and osmium polypyridyl complexes capable of targeting carbonic anhydrases are a major target in cancer therapy are described as new photosensitizers for photodynamic therapy.

Funder

H2020 European Research Council

Agence Nationale de la Recherche

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03932C

Reference73 articles.

1. Photodynamic Therapy: Current Status and Future Directions