Photo-cleavable purification/protection handle assisted synthesis of giant modified proteins with tandem repeats-Reference-Cited by-同舟云学术

Photo-cleavable purification/protection handle assisted synthesis of giant modified proteins with tandem repeats

Published:2019 Issue:37 Volume:10 Page:8694-8700
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Liu Xueyi¹²³⁴⁵,Liu Jiazhi¹²³⁴⁵,Wu Zhichao⁶⁷⁸⁹¹⁰,Chen Liangbiao⁶⁷⁸⁹¹⁰,Wang Siyao¹²³⁴⁵,Wang Ping¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs

2. School of Chemistry and Chemical Engineering

3. Shanghai Jiao Tong University

4. Shanghai 200240

5. P. R. China

6. Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources

7. Ministry of Education

8. College of Fisheries and Life Science

9. Shanghai Ocean University

10. Shanghai 201306

Abstract

A new N-terminal protection/purification handle (PPH), which contained a His₆tag for purification and a photo-cleavable linker, facilitates the efficient synthesis of large proteins with tandem repeats.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC03693H

Reference65 articles.

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