Redox-neutral rhodium(iii)-catalyzed chemo- and regiospecific [4 + 1] annulation between benzamides and alkenes for the synthesis of functionalized isoindolinones-Reference-Cited by-同舟云学术

Redox-neutral rhodium(iii)-catalyzed chemo- and regiospecific [4 + 1] annulation between benzamides and alkenes for the synthesis of functionalized isoindolinones

Published:2021 Issue:45 Volume:19 Page:9946-9952
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Qiao Jin¹²,Mao Hui¹^ORCID,Lu Shiyao²,Zhang Xiaoning²,Ni Hangcheng²^ORCID,Lu Yangbin²^ORCID

Affiliation:

1. College of Pharmacy, Jinhua Polytechnic, Jinhua 321007, P. R. China

2. Jinhua Branch, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Jinhua 321007, P. R. China

Abstract

A redox-neutral rhodium(iii)-catalyzed chemo- and regiospecific [4 + 1] annulation between benzamides and alkenes for the synthesis of functionalized isoindolinones has been achieved.

Funder

Natural Science Foundation of Zhejiang Province

Jinhua Science and Technology Bureau

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01792F

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2. Intramolecular Arylation of Tertiary Enamides through Pd(OAc)2-Catalyzed Dehydrogenative Cross-Coupling Reaction: Construction of Fused N-Heterocyclic Scaffolds and Synthesis of Isoindolobenzazepine Alkaloids

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4. Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction

5. Synthesis and biological evaluation of isoindoloisoquinolinone, pyroloisoquinolinone and benzoquinazolinone derivatives as poly(ADP-ribose) polymerase-1 inhibitors

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