Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity-Reference-Cited by-同舟云学术

Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity

Published:2021 Issue:2 Volume:57 Page:247-250
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sha Yong¹²³⁴⁵,Huang Ru¹²³⁴⁵,Huang Mengqi¹²³⁴⁵,Yue Huahua¹²³⁴⁵,Shan Yuanyue¹²³⁴⁵,Hu Jiaming¹²³⁴⁵,Xing Da¹²³⁴⁵^ORCID

Affiliation:

1. MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science

2. College of Biophotonics

3. South China Normal University

4. Guangzhou 510631

5. P. R. China

Abstract

A cascade CRISPR/cas nucleic acid diagnostic system, which can achieve high-sensitive and single-base specificity without target amplification, was developed for miRNA detection.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

China Postdoctoral Science Foundation

Guangzhou Science, Technology and Innovation Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D0CC06412B

Reference29 articles.

1. CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

2. CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

3. Cytosolic delivery of CRISPR/Cas9 ribonucleoproteins for genome editing using chitosan-coated red fluorescent protein

4. Development and Applications of CRISPR-Cas9 for Genome Engineering

5. DNAzyme activated protein-scaffolded CRISPR–Cas9 nanoassembly for genome editing

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