Rapid synthesis of isoquinolinones by intramolecular coupling of amides and ketones
Author:
Affiliation:
1. Institute of Drug Synthesis and Pharmaceutical Process
2. School of Pharmaceutical Sciences
3. Sun Yat-sen University
4. Guangzhou 510006
5. China
Abstract
Isoquinolinones were prepared in good yieldsviathe intramolecular coupling of amides and ketones in the presence of KOt-Bu/DMF.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB01948B
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