Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing 4-O-acetyl sialic acid
Author:
Affiliation:
1. Department of Chemistry
2. University of California
3. Davis
4. USA
5. School of Food Science
6. College of Plant Protection
Abstract
Chemoenzymatic synthesis: Monotreme milk glycans and other sialosides containing a 4-O-acetyl-sialic acid were synthesized in a gram or preparative scales using a one-pot two-enzyme sialylation system containing bacterial CMP-sialic acid synthetase and sialyltransferase PmST3.
Funder
National Cancer Institute
National Institute of General Medical Sciences
National Institute of Child Health and Human Development
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01706A
Reference51 articles.
1. Diversity in the sialic acids
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3. Advances in the Biology and Chemistry of Sialic Acids
4. Chemistry, Metabolism, and Biological Functions of Sialic Acids
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