Affiliation:
1. Department of Chemistry Federal Rural University of Pernambuco, UFRPE Dom Manoel de Medeiros Street, S/N° 52171-900 Recife Pernambuco Brazil
2. Department UACSA Federal Rural University of Pernambuco, UFRPE Cabo de Santo Agostinho 54518-430 Pernambuco Brazil
3. Centro de Educação e Saúde Universidade Federal de Campina Grande Olho D'agua da Bica, s/n Cuité 58175-000 PB Brazil
Abstract
AbstractN‐glycosides are produced when an aglycone is connected, for example, using a glycosylation reaction, to the sugar moiety via linkage of C−N bond at anomeric carbon. N‐glycosides are obtained from different precursors, including glucals, 1‐azido glycosides, glycosyl azide, glycosyl isothiocyanate, 2‐deoxy‐2‐iodo‐N‐glycoside, glycosyl‐1H‐1,2,3‐triazol, and 2‐nitroglucal. The biological relevance of N‐glycopyranosides has drowned attracted the attention of several researchers. The scope of this review covers the literature from 2010 to 2022. Recent advances focused on the natural occurrence, synthesis, mechanism, and pharmacological applications of N‐glycopyranosides are discussed.