Ruthenium(ii)-catalyzed [5 + 1] annulation reaction: a facile and efficient approach to construct 6-ethenyl phenanthridines utilizing a primary amine as a directing group-Reference-Cited by-同舟云学术

Ruthenium(ii)-catalyzed [5 + 1] annulation reaction: a facile and efficient approach to construct 6-ethenyl phenanthridines utilizing a primary amine as a directing group

Published:2020 Issue:19 Volume:7 Page:2944-2949
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Jian¹²³⁴⁵,Tang Baolan¹²³⁴⁵,Liu Xuexin¹²³⁴⁵,Lv Guanghui⁶⁷⁸⁹¹⁰,Shi Yuesen¹²³⁴⁵,Huang Tianle¹²³⁴⁵,Xing Huimin¹²³⁴⁵,Guo Xiaoyu¹²³⁴⁵,Hai Li¹²³⁴⁵^ORCID,Wu Yong¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Drug Targeting and Drug Delivery System of Education Ministry

2. Department of Medicinal Chemistry

3. West China School of Pharmacy

4. Sichuan University

5. Chengdu

6. Department of Pharmacy

7. Taihe Hospital

8. Hubei University of Medicine

9. Shiyan

10. China

Abstract

A ruthenium(ii)-catalyzed [5 + 1] annulation reaction between 2-arylanilines and cyclopropenones employing a free amine as a directing group has been developed.

Funder

Sichuan Province Science and Technology Support Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00769B

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3. Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors