Antitumour activities of sanguinarine and related alkaloids

Author:

Slaninová Iva,Pěnčíková Kristýna,Urbanová Jana,Slanina Jiří,Táborská Eva

Publisher

Springer Science and Business Media LLC

Subject

Plant Science,Biotechnology

Reference122 articles.

1. Aburai N, Yoshida M, Ohnishi M et al (2010) Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells. Biosci Biotechnol Biochem 74:548–552

2. Adhami VM, Aziz MH, Mukhtar H et al (2003) Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes. Clin Cancer Res 9:3176–3182

3. Adhami VM, Aziz MH, Reagan-Shaw SR et al (2004) Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery. Mol Cancer Ther 3:933–940

4. Adhikari A, Hossain M, Maiti M et al (2008) Energetics of the binding of phototoxic and cytotoxic plant alkaloid sanguinarine to DNA: isothermal titration calorimetric studies. J Mol Struct 889:54–63

5. Ahmad N, Gupta S, Husain MM et al (2000) Differential anti-proliferative and apoptotic response of sanguinarine for cancer cells versus normal cells. Clin Cancer Res 6:1524–1528

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