Coacervate microdroplet protocell-mediated gene transfection for nitric oxide production and induction of cell apoptosis-Reference-Cited by-同舟云学术

Coacervate microdroplet protocell-mediated gene transfection for nitric oxide production and induction of cell apoptosis

Published:2021 Issue:47 Volume:9 Page:9784-9793
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhang Yanwen¹,Yao Yu¹,Liu Songyang¹,Chen Yufeng¹,Zhou Shaohong¹,Wang Kemin¹^ORCID,Yang Xiaohai¹^ORCID,Liu Jianbo¹^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China

Abstract

The cellular internalization of pNOS-containing coacervate carriers resulted in high NOS expression and NO overproduction, which suggests the incorporation of genes in coacervates as a viable and novel strategy for developing cargo biocarriers.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01930A

Reference48 articles.

1. Compartmentalised RNA catalysis in membrane-free coacervate protocells

2. Oligonucleotide–Peptide Complexes: Phase Control by Hybridization