Surface chemistry mediates the tumor entrance of nanoparticles probed using single-molecule dual-imaging nanodots-Reference-Cited by-同舟云学术

Surface chemistry mediates the tumor entrance of nanoparticles probed using single-molecule dual-imaging nanodots

Published:2023 Issue:21 Volume:11 Page:7051-7061
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Ren Huiming¹^ORCID,Hu Qiuhui¹²,Sun Yuji¹,Zhou Xiaoxuan²,Zhu Yincong¹,Dong Qiuyang¹,Chen Linying¹,Tang Jianbin¹^ORCID,Hu Hongjie²,Shen Youqing¹^ORCID,Zhou Zhuxian¹^ORCID

Affiliation:

1. Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China

2. Department of Radiology, Sir Run Run Shaw Hospital (SRRSH) of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310027, China

Abstract

We develop single-molecule dual-imaging nanodots by divergent growth for fluorescence and MR imaging of surface chemistry-dependent tumor entrance. The results show that the surface chemistry of nanoparticles can dominate the ways of tumor entrance.

Funder

National Key Research and Development Program of China

Primary Research and Development Plan of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM01171B

Reference36 articles.

1. The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives