Rational design of polymer-based mRNA delivery systems for cancer treatment-Reference-Cited by-同舟云学术

Rational design of polymer-based mRNA delivery systems for cancer treatment

Published:2024 Issue:24 Volume:15 Page:2437-2456
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Wan Qianyu¹²,Sun Yuji¹,Sun Xuanrong²^ORCID,Zhou Zhuxian¹^ORCID

Affiliation:

1. Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China

2. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals and College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China

Abstract

This review introduces the basic design principles and recent advances in polymeric mRNA therapeutics, highlighting strategies to realize cancer-selective, organ-targeted, and tissue-penetrating mRNA delivery.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/PY/D4PY00206G

Reference185 articles.

1. Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them

2. Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria

3. A new developing class of gene delivery: messenger RNA-based therapeutics

4. mRNA-based therapeutics — developing a new class of drugs

5. Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

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