Design, synthesis and evaluation of seleno-dihydropyrimidinones as potential multi-targeted therapeutics for Alzheimer's disease

Author:

Canto Rômulo F. S.12345,Barbosa Flavio A. R.12345,Nascimento Vanessa12345,de Oliveira Aldo S.6345,Brighente Inês M. C.6345,Braga Antonio Luiz12345

Affiliation:

1. Laboratorio de Sintese de Substancias de Selenio Bioativas

2. Centro de Ciencias Fisicas e Matematicas

3. Departamento de Quimica

4. Universidade Federal de Santa Catarina

5. Florianopolis, Brazil

6. CFM

Abstract

We report the design, synthesis and evaluation of a series of seleno-dihydropyrimidinones as potential multi-targeted therapeutics for Alzheimer's disease.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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