First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT<sub>6</sub> Agents with a Beneficial Neuroprotective Profile against Alzheimer’s Disease-Reference-Cited by-同舟云学术

First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT₆ Agents with a Beneficial Neuroprotective Profile against Alzheimer’s Disease

Published:2024-01-08 Issue:2 Volume:67 Page:1580-1610
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pyka Patryk¹²³,Haberek Wawrzyniec¹²³,Więcek Małgorzata¹,Szymanska Ewa¹^ORCID,Ali Wesam¹²,Cios Agnieszka⁴,Jastrzębska-Więsek Magdalena⁴^ORCID,Satała Grzegorz⁵^ORCID,Podlewska Sabina⁵^ORCID,Di Giacomo Silvia⁶⁷,Di Sotto Antonella⁶,Garbo Sabrina⁸,Karcz Tadeusz¹,Lambona Chiara⁹^ORCID,Marocco Francesco⁸^ORCID,Latacz Gniewomir¹,Sudoł-Tałaj Sylwia¹³,Mordyl Barbara¹⁰,Głuch-Lutwin Monika¹⁰,Siwek Agata¹⁰,Czarnota-Łydka Kinga¹³,Gogola Dawid¹³,Olejarz-Maciej Agnieszka¹,Wilczyńska-Zawal Natalia⁴,Honkisz-Orzechowska Ewelina¹,Starek Małgorzata¹¹,Dąbrowska Monika¹¹,Kucwaj-Brysz Katarzyna¹,Fioravanti Rossella⁹,Nasim Muhammad Jawad²^ORCID,Hittinger Marius¹²¹³,Partyka Anna⁴,Wesołowska Anna⁴,Battistelli Cecilia⁸,Zwergel Clemens²⁹¹²^ORCID,Handzlik Jadwiga¹

Affiliation:

1. Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

2. Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B 2.1, D-66123 Saarbrücken, Germany

3. Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, św. Łazarza 15, 31-530 Kraków, Poland

4. Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

5. Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland

6. Department of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy

7. Italian National Institute of Health (ISS), Viale Regina Elena 299, 00161 Rome, Italy

8. Department of Molecular Medicine, Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy

9. Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy

10. Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

11. Department of Inorganic and Analytical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

12. Department of Drug Discovery, Pharmbiotec gGmbH, Nußkopf 39, 66578 Schiffweiler, Germany

13. Department of Drug Delivery, Pharmbiotec gGmbH, Nußkopf 39, 66578 Schiffweiler, Germany

Funder

Wydzial Lekarski, Uniwersytet Jagiellonski Collegium Medicum

Sapienza Universit? di Roma

European Regional Development Fund

Narodowe Centrum Nauki

Ministero dell'Universit? e della Ricerca

KOHR GmbH

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02148

Reference131 articles.

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