Tandem radical cyclization of N-methacryloyl benzamides with CBr4 to construct brominated isoquinolinediones
Author:
Affiliation:
1. Key Laboratory of Eco-Environment-Related Polymer Materials Ministry of Education
2. College of Chemistry and Chemical Engineering
3. Northwest Normal University
4. Lanzhou
5. China
Abstract
Cumene promoted auto-oxidation involved tandem radical cyclization of N-methacryloyl benzamides using CBr4 as the bromine source to construct brominated isoquinolinediones is described.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01964A
Reference45 articles.
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3. Discovery of 4-(Benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(Pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4
4. 4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4 (CDK4)
5. Aerobic oxidative cyclization of benzamides via meta-selective C–H tert-alkylation: rapid entry to 7-alkylated isoquinolinediones
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