The renaissance of strained 1-azabicyclo[1.1.0]butanes as useful reagents for the synthesis of functionalized azetidines
Author:
Affiliation:
1. Department of Pharmacy - Drug Sciences
2. University of Bari “A. Moro” Via E. Orabona 4
3. Bari 70125
4. Italy
Abstract
Since their discovery in the late 1960s, 1-azabicyclo[1.1.0]butanes have demonstrated to be interesting precursors of azetidines, because of the peculiar reactivity of the C3–N bond that allows double functionalization in the 1,3 positions.
Funder
Universita degli Studi di Bari Aldo Moro
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01251C
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