Mitigating Heterocycle Metabolism in Drug Discovery
Author:
Affiliation:
1. Department of Therapeutic Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm300343m
Reference87 articles.
1. Role of drug metabolism in drug discovery and development
2. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics
3. Pharmacokinetics and its role in small molecule drug discovery research
4. Optimization of metabolic stability as a goal of modern drug design
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