Ruthenium arene complexes with triphenylphosphane ligands: cytotoxicity towards pancreatic cancer cells, interaction with model proteins, and effect of ethacrynic acid substitution-Reference-Cited by-同舟云学术

Ruthenium arene complexes with triphenylphosphane ligands: cytotoxicity towards pancreatic cancer cells, interaction with model proteins, and effect of ethacrynic acid substitution

Published:2017 Issue:23 Volume:41 Page:14574-14588
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Biancalana Lorenzo¹²³⁴,Pratesi Alessandro⁵⁶⁷⁸⁴^ORCID,Chiellini Federica¹²³⁴,Zacchini Stefano⁹¹⁰¹¹⁴^ORCID,Funaioli Tiziana¹²³⁴,Gabbiani Chiara¹²³⁴^ORCID,Marchetti Fabio¹²³⁴^ORCID

Affiliation:

1. Dipartimento di Chimica e Chimica Industriale

2. Università di Pisa

3. I-56124 Pisa

4. Italy

5. MetMed

6. Dipartimento di Chimica “Ugo Schiff”

7. Università di Firenze

8. I-50019 Sesto Fiorentino

9. Dipartimento di Chimica Industriale “Toso Montanari”

10. Università di Bologna

11. I-40136 Bologna

Abstract

The anticancer behaviour of Ru arene complexes can be tuned by an appropriate choice of the site and linkage of the bioactive group to the phosphane ligand.

Funder

Universitá di Pisa

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ02300F

Reference77 articles.

1. Thirty Years of the Drug Candidate NAMI‐A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective

2. X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

3. NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

4. I. Bratsos , T.Gianferrara , E.Alessio , C. G.Hartinger , M. A.Jakupec and B. K.Keppler , in Bioinorganic Medicinal Chemistry , ed. E. Alessio , Wiley-VCH , Weinheim , 2011 , pp. 151–174

5. Recent advances in supramolecular and biological aspects of arene ruthenium(II) complexes

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