X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism-Reference-Cited by-同舟云学术

X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

Published:2016-06-07 Issue:12 Volume:59 Page:5894-5903
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bijelic Aleksandar¹,Theiner Sarah,Keppler Bernhard K.,Rompel Annette¹

Affiliation:

1. Fakultät für Chemie, Institut für Biophysikalische Chemie, Universität Wien, Althanstraße 14, 1090 Wien, Austria

Funder

Austrian Science Fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00600

Reference75 articles.

1. Dabrowiak, J. C.Metals in Medicine;John Wiley & Sons:Hoboken, NJ, 2013; pp151–161.

2. Cisplatin Nephrotoxicity: A Review

3. Balcerzak, M.Quantification of Noble Metals in Biological and Environmental Samples. InHandbook of Trace Analysis;Baranowska, I., Ed.Springer:Berlin, 2016; pp371–402.

4. Intrinsic and Acquired Forms of Resistance against the Anticancer Ruthenium Compound KP1019 [Indazoliumtrans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A)

Cited by 115 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New Ru(II)-p-cymene compounds bearing indomethacin and indomethacin-pyridineamide ligands: synthesis, characterization, computational studies and investigation of their interactions with the Human Serum Albumin;Inorganica Chimica Acta;2024-07

2. Exploring the coordination chemistry of ruthenium complexes with lysozymes: structural and in-solution studies;Frontiers in Chemistry;2024-04-04

3. Riding the metal wave: A review of the latest developments in metal-based anticancer agents;Coordination Chemistry Reviews;2024-02

4. Synthesis and preclinical evaluation of BOLD-100 radiolabeled with ruthenium-97 and ruthenium-103;Dalton Transactions;2024

5. Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections;Pharmaceuticals;2023-12-15