Manganese- and rhenium-catalyzed C–H enaminylation: expedient access to novel indole–purine hybrids with anti-tumor bioactivities-Reference-Cited by-同舟云学术

Manganese- and rhenium-catalyzed C–H enaminylation: expedient access to novel indole–purine hybrids with anti-tumor bioactivities

Published:2020 Issue:22 Volume:7 Page:3709-3714
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xu Zhongnan¹²³⁴⁵,Wang Yuqing¹²³⁴⁵,Zheng Yucheng¹²³⁴⁵,Huang Zhixing¹²³⁴⁵,Ackermann Lutz⁶⁷⁸⁹¹⁰^ORCID,Ruan Zhixiong¹²³⁴⁵^ORCID

Affiliation:

1. The Fifth Affiliated Hospital

2. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease

3. School of Pharmaceutical Sciences

4. Guangzhou Medical University

5. Guangzhou

6. Institut für Organische und Biomolekulare Chemie

7. Georg-August-Universität Göttingen

8. 37077 Göttingen

9. Germany

10. WISCh (Wöhler-Research Institute for Sustainable Chemistry)

Abstract

The C–H enaminylation of novel 6-(1H-indol-1-yl)-purines with ketenimines was accomplished by means of aqueous manganese and rhenium catalysis, which sets the stage for the facile synthesis of indole–purine hybrids with anti-tumor bioactivities.

Funder

Georg-August-Universität Göttingen

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO01120G

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