Controllable synthesis of pyrido[2,3-b]indol-4-ones or indolo[3,2-b]quinolines via formal intramolecular C(sp2)–H functionalization
Author:
Affiliation:
1. Shanghai Key Laboratory of Green Chemistry and Chemical Processes
2. School of Chemistry and Molecular Engineering
3. East China Normal University
4. Shanghai
5. China
6. School of Chemistry and Chemical Engineering
7. Linyi University
8. Linyi
Abstract
An atom-economical Fe-catalyzed protocol for the controllable synthesis of pyrido[2,3-b]indol-4-ones or indolo[3,2-b]quinolines through C–H/N–H coupling reactions. The natural product quindolinone was conveniently prepared by this reaction.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB02108F
Reference46 articles.
1. Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2. Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
3. Indoles in Multicomponent Processes (MCPs)
4. Constructing Iboga Alkaloids via C–H Bond Functionalization: Examination of the Direct and Catalytic Union of Heteroarenes and Isoquinuclidine Alkenes
5. Solid-Phase Synthesis of Biologically Active Benzoannelated Nitrogen Heterocycles: An Update
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