Nickel-catalyzed defluorinative alkylation of C(sp2)–F bonds-Reference-Cited by-同舟云学术

Nickel-catalyzed defluorinative alkylation of C(sp2)–F bonds

Published:2021 Issue:16 Volume:8 Page:4533-4542
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Tong Xue¹²³⁴⁵,Luo Si-Si¹²³⁴⁵,Shen Hua¹²³⁴⁵,Zhang Shu¹²³⁴⁵,Cao Tian¹²³⁴⁵,Luo Yi-Peng¹²³⁴⁵,Huang Long-Ling¹²³⁴⁵,Ma Xi-Tao⁶⁷⁵,Liu Xiang-Wei¹²³⁴⁵^ORCID

Affiliation:

1. Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs

2. School of Life Science and Engineering

3. Southwest Jiaotong University

4. Chengdu 610031

5. China

6. Hospital of Chengdu University of Traditional Chinese Medicine

7. Chengdu 610072

Abstract

A nickel-catalyzed defluorinative alkylation of unactivated C(sp²)–F electrophiles using commercially available trialkylaluminum reagents, thus forming the C(sp²)–C(sp³) bonds is reported.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Fundamental Research Funds for the Central Universities

1000 Talents Sichuan Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00549A

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