Efficient access to enantiopure 1,3-disubstituted isoindolines from selective catalytic fragmentation of an original desymmetrized rigid overbred template-Reference-Cited by-同舟云学术

Efficient access to enantiopure 1,3-disubstituted isoindolines from selective catalytic fragmentation of an original desymmetrized rigid overbred template

Published:2015 Issue:15 Volume:13 Page:4438-4448
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pandey Ganesh¹²³⁴⁵,Varkhedkar Rajesh¹²³⁴⁵,Tiwari Divya¹²³⁴⁵

Affiliation:

1. Molecular Synthesis Laboratory

2. Centre of Biomedical Research (CBMR)

3. Sanjay Gandhi Post-Graduate Institute of Medical Sciences Campus

4. Lucknow-226 014

5. India

Abstract

Enantiopure 1,3-disubstituted isoindolines are synthesized from selective C–C bond fragmentation of a rigid overbred template, obtained through an asymmetric desymmetrization reaction.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00229J

Reference39 articles.

1. 1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

2. An Efficient and Cost-Effective Synthesis of Pagoclone

3. (±)-Nuevamine, an isoindoloisoquinoline alkaloid, and (±)-lennoxamine, an isoindolobenzazepine

4. Novel Multidrug Resistance Reversal Agents

5. Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone

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