A palladium catalyzed asymmetric desymmetrization approach to enantioenriched 1,3-disubstituted isoindolines-Reference-Cited by-同舟云学术

A palladium catalyzed asymmetric desymmetrization approach to enantioenriched 1,3-disubstituted isoindolines

Published:2023 Issue:40 Volume:14 Page:11267-11272
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Dethe Dattatraya H.¹^ORCID,Kumar Vimlesh¹,Shukla Manmohan¹

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur - 208016, India

Abstract

Herein, we report the first palladium/MPAA catalyzed enantioselective C–H activation/[4 + 1] annulation of diarylmethyltriflamide and olefins to construct chiral cis-1,3-disubstituted isoindoline derivatives.

Funder

Science and Engineering Research Board

Indian Institute of Technology Kanpur

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03496H

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