An efficient one-pot decarboxylative aromatization of tetrahydro-β-carbolines by using N-chlorosuccinimide: total synthesis of norharmane, harmane and eudistomins-Reference-Cited by-同舟云学术

An efficient one-pot decarboxylative aromatization of tetrahydro-β-carbolines by using N-chlorosuccinimide: total synthesis of norharmane, harmane and eudistomins

Published:2015 Issue:109 Volume:5 Page:90121-90126
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kamal Ahmed¹²³⁴⁵,Sathish Manda¹²³⁴,Prasanthi A. V. G.⁵⁶⁷⁴,Chetna Jadala⁵⁶⁷⁴,Tangella Yellaiah¹²³⁴,Srinivasulu Vunnam¹²³⁴,Shankaraiah Nagula⁵⁶⁷⁴,Alarifi Abdullah⁸⁹¹⁰¹¹¹²

Affiliation:

1. Medicinal Chemistry & Pharmacology

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500 007

4. India

5. Department of Medicinal Chemistry

6. National Institute of Pharmaceutical Education and Research (NIPER)

7. Hyderabad-500 037

8. Catalytic Chemistry Research Chair

9. Chemistry Department

10. College of Science

11. King Saud University

12. Riyadh 11451

Abstract

A mild one-pot synthesis of β-carbolines from their tetrahydro-β-carboline acids has been developed via decorboxylative aromatization using N-chlorosuccinimide (NCS).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16221A

Reference89 articles.

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4. A review on medicinal importance, pharmacological activity and bioanalytical aspects of beta-carboline alkaloid “Harmine”

5. Eudistomin V, a New β-Carboline from the Australian Ascidian Pseudodistoma aureum

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