Ring-opening fluorination of bicyclic azaarenes-Reference-Cited by-同舟云学术

Ring-opening fluorination of bicyclic azaarenes

Published:2022 Issue:3 Volume:13 Page:665-670
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Komatsuda Masaaki¹^ORCID,Suto Ayane¹,Kondo Hiroki¹,Takada Hiroyuki²^ORCID,Kato Kenta¹^ORCID,Saito Bunnai²,Yamaguchi Junichiro¹^ORCID

Affiliation:

1. Department of Applied Chemistry, Waseda University, 513, Wasedatsurumakicho, Shinjuku, Tokyo 169-8555, Japan

2. Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan

Abstract

A ring-opening fluorination of bicyclic azaarenes was developed. Although this overall transformation can be classified as an electrophilic fluorination of aromatics, it is a novel type of fluorination that results in construction of tert-C–F bonds.

Funder

Japan Society for the Promotion of Science

Exploratory Research for Advanced Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC06273E

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