Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles-Reference-Cited by-同舟云学术

Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles

Published:2018 Issue:47 Volume:8 Page:26523-26527
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Venkateswarlu Vunnam¹²³⁴⁵,Kour Jaspreet¹²³⁴⁵,Kumar K. A. Aravinda¹²³⁴,Verma Praveen Kumar¹²³⁴,Reddy G. Lakshma¹²³⁴⁵,Hussain Yaseen¹²³⁴⁵,Tabassum Aliya¹²³⁴,Balgotra Shilpi¹²³⁴⁵,Gupta Sorav¹²³⁴⁵,Hudwekar Abhinandan D.¹²³⁴⁵,Vishwakarma Ram A.¹²³⁴,Sawant Sanghapal D.¹²³⁴⁵^ORCID

Affiliation:

1. Medicinal Chemistry Division

2. CSIR-Indian Institute of Integrative Medicine

3. Jammu-180001

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

The synthesis of tri-substituted pyrazoles was achieved via direct N-heterocyclization of hydrazines with metal-acetylacetonate and -dibenzylideneacetonate without using any base or additives under microwave irradiation in a single step.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA04550J

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3. SAR of a novel ‘Anthranilamide Like’ series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer