Highly diastereoselective synthesis of vicinal diamines via a Rh-catalyzed three-component reaction of diazo compounds with diarylmethanimines and ketimines-Reference-Cited by-同舟云学术

Highly diastereoselective synthesis of vicinal diamines via a Rh-catalyzed three-component reaction of diazo compounds with diarylmethanimines and ketimines

Published:2021 Issue:12 Volume:8 Page:2997-3003
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhou Kai¹²³⁴⁵^ORCID,Bao Ming¹²³⁴⁵^ORCID,Sha Hongkai¹²³⁴⁵,Dong Guizhi¹²³⁴⁵,Hong Kemiao¹²³⁴⁵,Xu Xinfang¹²³⁴⁵^ORCID,Hu Wenhao¹²³⁴⁵

Affiliation:

1. Guangdong Key Laboratory of Chiral Molecule and Drug Discovery

2. School of Pharmaceutical Sciences

3. Sun Yat-sen University

4. Guangzhou 510006

5. China

Abstract

A Rh-catalyzed selective three-component reaction of diazo compounds with diarylmethanimines and ketimines is reported that offers an efficient and convenient access to vicinal diamine derivatives with two tertiary stereocenters in high yields.

Funder

National Natural Science Foundation of China

National Postdoctoral Program for Innovative Talents

Guangdong Province Introduction of Innovative R&D Team

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00083G

Reference75 articles.

1. Privileged Chiral Catalysts