Chemoenzymatic synthesis of optically active phenolic 3,4-dihydropyridin-2-ones: a way to access enantioenriched 1,4-dihydropyridine and benzodiazepine derivatives-Reference-Cited by-同舟云学术

Chemoenzymatic synthesis of optically active phenolic 3,4-dihydropyridin-2-ones: a way to access enantioenriched 1,4-dihydropyridine and benzodiazepine derivatives

Published:2017 Issue:24 Volume:15 Page:5171-5181
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Torres Susana Y.¹²³⁴⁵,Brieva Rosario¹²³⁴,Rebolledo Francisca¹²³⁴^ORCID

Affiliation:

1. Departamento de Química Orgánica e Inorgánica and Instituto Universitario de Biotecnología de Asturias

2. Universidad de Oviedo

3. 33006-Oviedo

4. Spain

5. Laboratorio de Síntesis Orgánica

Abstract

Kinetic resolution of 3,4-DHP-2-ones with Candida rugose lipase (CRL) has been possible due to the presence of a reactive phenolic ester in a remote position.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01066D

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1. Highly efficient and concise synthesis of both antipodes of SB204900, clausenamide, neoclausenamide, homoclausenamide and ζ-clausenamide. Implication of biosynthetic pathways of clausena alkaloids

2. Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

3. Selective α1a adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones

4. Pilot-Plant Preparation of 3,4-Dihydropyridin-2-one Derivatives, the Core Structures of P2X7Receptor Antagonists

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