1. Departments of Medicinal Chemistry, Biology, and Drug Metabolism and Pharmacokinetics, Cardiovascular and Urogential Center of Excellence in Drug Discovery, Departments of Computational, Analytical, and Structural Sciences, Gene Expression and Protein Biochemistry, High Throughput Chemistry, and Screening and Compound Profiling, Discovery Research, GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, King of Prussia, Pennsylvania 19406