Deracemization of 1-phenylethanols in a one-pot process combining Mn-driven oxidation with enzymatic reduction utilizing a compartmentalization technique-Reference-Cited by-同舟云学术

Deracemization of 1-phenylethanols in a one-pot process combining Mn-driven oxidation with enzymatic reduction utilizing a compartmentalization technique

Published:2022 Issue:17 Volume:12 Page:10619-10624
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sato Hirofumi¹^ORCID,Yamada Rei²,Watanabe Yomi¹,Kiryu Takaaki¹,Kawano Shintaro¹^ORCID,Shizuma Motohiro¹^ORCID,Kawasaki Hideya²^ORCID

Affiliation:

1. Osaka Research Institute of Industrial Science and Technology, 1-6-50 Morinomiya, Joto-ku, Osaka 536-8553, Japan

2. Kansai University, 3-3-35 Yamatecho, Suita, Osaka 564-8680, Japan

Abstract

PDMS thimble was the key to combining incompatible reactions to achieve deracemization of 1-phenylethanols in high yield with high optical yield.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA01326F

Reference49 articles.

1. Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals

2. Synthesis of chiral pharmaceutical intermediates by biocatalysis

3. N.Arai and T.Ohkuma , Reduction of Carbonyl Groups: Hydrogenation , ed. G. A. Molander , Thieme , New York , 2011 , vol. 2.1 , p. 9

4. Industrial Methods for the Production of Optically Active Intermediates

5. Application of Ketoreductase in Asymmetric Synthesis of Pharmaceuticals and Bioactive Molecules: An Update (2018–2020)

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Classification and functional origins of stereocomplementary alcohol dehydrogenases for asymmetric synthesis of chiral secondary alcohols: A review;International Journal of Biological Macromolecules;2024-06

2. Design of 3D‐Printed Heterogeneous Reactor Systems To Overcome Incompatibility Hurdles when Combining Metal and Enzyme Catalysis in a One‐Pot Process;Angewandte Chemie International Edition;2024-05-03

3. Design von 3D‐gedruckten heterogenen Reaktorsystemen zur Überwindung von Inkompatibilitätshürden bei der Kombination von Metall‐ und Enzym‐Katalyse in einem Eintopf‐Prozess;Angewandte Chemie;2024-05-03

4. One-pot chemo- and photo-enzymatic linear cascade processes;Chemical Society Reviews;2024

5. Asymmetric Chemoenzymatic One-Pot Synthesis: Process Concepts & Recent Progress in Combining Chemo- & Biocatalytic Reactions for the Formation of Chiral Molecules;Comprehensive Chirality;2024