Facile access to a heterocyclic, sp3-rich chemical scaffold via a tandem condensation/intramolecular nitrone–alkene [3+2] cycloaddition strategy-Reference-Cited by-同舟云学术

Facile access to a heterocyclic, sp3-rich chemical scaffold via a tandem condensation/intramolecular nitrone–alkene [3+2] cycloaddition strategy

Published:2015 Issue:64 Volume:51 Page:12867-12870
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Rawling M. J.¹²³⁴,Storr T. E.¹²³⁴,Bawazir W. A.¹²³⁴⁵,Cully S. J.¹²³⁴,Lewis W.¹²³⁴,Makki M. S. I. T.⁵⁶⁷⁸⁹,Strutt I. R.¹⁰¹¹³⁴,Jones G.¹⁰¹¹³⁴,Hamza D.¹⁰¹¹³⁴,Stockman R. A.¹²³⁴

Affiliation:

1. School of Chemistry

2. University of Nottingham

3. Nottingham

4. UK

5. Department of Chemistry

6. Faculty of Science

7. King Abdul-Aziz University

8. Jeddah 21315

9. Saudi Arabia

10. Sygnature Discovery Limited

11. BioCity

Abstract

A heterocyclic, sp³-rich chemical scaffold was synthesised in just 6 steps via a highly regio- and diastereo-selective tandem nitrone formation/intramolecular nitrone–alkene [3+2] cycloaddition reaction.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC05070G

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