Disturbed mitochondrial quality control involved in hepatocytotoxicity induced by silica nanoparticles-Reference-Cited by-同舟云学术

Disturbed mitochondrial quality control involved in hepatocytotoxicity induced by silica nanoparticles

Published:2020 Issue:24 Volume:12 Page:13034-13045
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Qi Yi¹²³⁴⁵,Ma Ru¹²³⁴⁵,Li Xueyan¹²³⁴⁵,Lv Songqing⁶³⁴⁵⁷,Liu Xiaoying⁶³⁴⁵⁷,Abulikemu Alimire¹²³⁴⁵,Zhao Xinying⁶³⁴⁵⁷,Li Yanbo⁶³⁴⁵⁷,Guo Caixia¹²³⁴⁵^ORCID,Sun Zhiwei⁶³⁴⁵⁷

Affiliation:

1. Department of Occupational Health and Environmental Health

2. School of Public Health

3. Capital Medical University

4. Beijing

5. China

6. Beijing Key Laboratory of Environmental Toxicology

7. Department of Toxicology and Sanitary Chemistry

Abstract

SiNPs triggered hepatocytotoxicity through interfering mitochondrial quality control process, including imbalanced mitochondrial dynamics, disturbed mitophagy and suppressed biogenesis, leading to mitochondrial dysfunction and ensuing cell damage.

Funder

National Natural Science Foundation of China

Beijing Municipal Commission of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR01893G

Reference77 articles.

1. Nanoengineered silica: Properties, applications and toxicity

2. Detection and Characterization of SiO2 and TiO2 Nanostructures in Dietary Supplements