Identification of a highly promiscuous glucosyltransferase from <i>Penstemon barbatus</i> for natural product glycodiversification-Reference-Cited by-同舟云学术

Identification of a highly promiscuous glucosyltransferase from Penstemon barbatus for natural product glycodiversification

Published:2023 Issue:21 Volume:21 Page:4445-4454
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wu Yanan¹²³,Yang Yihan²³^ORCID,Du Liping¹,Zhuang Yibin²³^ORCID,Liu Tao²³

Affiliation:

1. Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China

2. Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China

3. National Center of Technology Innovation for Synthetic Biology, Tianjin 300308, China

Abstract

A new glycosyltransferase UGT84A95 was discovered from Penstemon barbatus and exhibited broad substrate specificity toward various phenylethanoid glycosides, flavonoids, terpenoids, stilbene glycosides, coumarins, and simple polyphenols.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00370A

Reference34 articles.

1. Phenylethanoid Glycosides: Research Advances in Their Phytochemistry, Pharmacological Activity and Pharmacokinetics

2. A review on the structure and pharmacological activity of phenylethanoid glycosides

3. Therapeutic potential of phenylethanoid glycosides: A systematic review

4. Advances in Enzymatic Glycoside Synthesis

5. Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts

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