Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies-Reference-Cited by-同舟云学术

Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies

Published:2020 Issue:21 Volume:12 Page:11672-11683
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kim Baksun¹²³⁴,Shin Jaeho¹²³⁴,Kiziltepe Tanyel¹²³⁴⁵,Bilgicer Basar¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering

2. University of Notre Dame

3. Notre Dame

4. USA

5. Harper Cancer Research Institute

Abstract

Optimized TNP formulation using peptide (PV3), which we identified, enhanced selectivity for CD22+ malignant B cells over healthy B cells.

Funder

Walther Cancer Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR02133D

Reference46 articles.

1. Targeted liposomal drug delivery systems for the treatment of B cell malignancies

2. Rituximab in B-Cell Hematologic Malignancies: A Review of 20 Years of Clinical Experience

3. Novel and emerging therapies for B cell lymphoma

4. Overview of Targeted Drugs for Mature B-Cell Non-hodgkin Lymphomas

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