A sensing system constructed by combining a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification for highly sensitive miRNA detection-Reference-Cited by-同舟云学术

A sensing system constructed by combining a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification for highly sensitive miRNA detection

Published:2022 Issue:9 Volume:147 Page:1937-1943
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Sun Shujuan¹^ORCID,Wang Wenqing¹,Hu Xuemei²,Zheng Cheng²,Xiang Qi¹²,Yang Qingguo²,Zhang Jing²,Shen Zhi-Fa²,Wu Zai-Sheng¹^ORCID

Affiliation:

1. Cancer Metastasis Alert and Prevention Center, Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 305108, China

2. Zhejiang Provincial Key Laboratory of Medical Genetics, Key Laboratory of Laboratory Medicine, Ministry of Education, China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China

Abstract

A novel amplification assay strategy is developed for the highly sensitive detection of miRNA-21 based on a combination of a structure-switchable molecular beacon with nicking-enhanced rolling circle amplification.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D1AN02218K

Reference59 articles.

1. Non-coding RNAs in human disease