Novel 99mTc-labelled complexes with thymidine isocyanide: radiosynthesis and evaluation as potential tumor imaging tracers

Author:

Duan Xiaojiang12345,Zhang Xuran12345,Gan Qianqian12345,Fang Si'an12345,Ruan Qing12345,Song Xiaoqing12345,Zhang Junbo12345ORCID

Affiliation:

1. Key Laboratory of Radiopharmaceuticals

2. Ministry of Education

3. College of Chemistry

4. Beijing Normal University

5. Beijing 100875

Abstract

SPECT/CT image of 12 in mice bearing S180 at 1 h p.i.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Reference37 articles.

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2. Z. W. F. Kandeel , in Molecular Imaging Probes for Cancer Research , ed. X. Chen , World Scientific Publishing , Singapore , 2012 , ch. 8, p. 219

3. N3-substituted thymidine bioconjugates for cancer therapy and imaging

4. Imaging proliferation in vivo with [F-18]FLT and positron emission tomography

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