Small molecules aimed at type III secretion systems to inhibit bacterial virulence-Reference-Cited by-同舟云学术

Small molecules aimed at type III secretion systems to inhibit bacterial virulence

Published:2013 Issue:1 Volume:4 Page:68-79
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Tsou Lun K.¹²³⁴,Dossa Paul D.¹²³⁴,Hang Howard C.¹²³⁴

Affiliation:

1. Laboratory of Chemical Biology and Microbial Pathogenesis

2. The Rockefeller University

3. New York

4. USA

Abstract

The development of new anti-bacterial compounds presents a major challenge to modern medicine as bacterial strains resistant to traditional antibiotics are constantly emerging.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2013/MD/C2MD20213A

Reference69 articles.

1. Anti-virulence strategies to combat bacteria-mediated disease

2. Targeting virulence: a new paradigm for antimicrobial therapy

3. Interactions Between the Microbiota and the Immune System

4. Shifting the balance: antibiotic effects on host–microbiota mutualism

5. Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

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