An albumin-binding Gd-HPDO3A contrast agent for improved intravascular retention-Reference-Cited by-同舟云学术

An albumin-binding Gd-HPDO3A contrast agent for improved intravascular retention

Published:2021 Issue:17 Volume:8 Page:4014-4025
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Tear Louise R.¹,Carrera Carla²^ORCID,Dhakan Chetan B.²³,Cavallari Eleonora¹,Travagin Fabio⁴,Calcagno Claudia⁵,Aime Silvio¹²,Gianolio Eliana¹²^ORCID

Affiliation:

1. Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino Via Nizza 52, 10126 Torino, Italy

2. Institute of Biostructures and Bioimaging (IBB), Italian National Research Council (CNR), Turin, Italy

3. University of Campania “Luigi Vanvitelli”, Napoli, Italy

4. Dipartimento di Scienze del Farmaco (DSF), Università del Piemonte Orientale “A. Avogadro”, Novara, Italy

5. BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Abstract

A new Gd-HPDO3A derivative with improved MR contrast enhancing efficiency, demonstrated in a murine tumor model and in mouse models for stable and vulnerable atherosclerotic plaques, due to increased intravascular retention.

Funder

Regione Piemonte

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QI/D1QI00128K

Reference56 articles.

1. Blood pool contrast agents for venous magnetic resonance imaging

2. P.Caravan , Cardiovascular Magnetic Resonance Contrast Agents in Cardiovasc. Magn. Reson , ed. W. J. Manning and D. J. Pennell , Elsevier , 2010 , pp. 76–90

3. Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A novel albumin-binding macrocyclic Gd-HPDO3A complex bearing a deoxycholic acid residue: the role of the hydration state, water exchange and local dynamics in the observed relaxivity;Inorganic Chemistry Frontiers;2024

2. Seeking for Innovation with Magnetic Resonance Imaging Paramagnetic Contrast Agents: Relaxation Enhancement via Weak and Dynamic Electrostatic Interactions with Positively Charged Groups on Endogenous Macromolecules;Journal of the American Chemical Society;2023-12-28

3. Luminescence and magnetic properties of bifunctional nanoparticles composited by nitrogen-doped graphene quantum dots and gadolinium;Journal of Rare Earths;2023-05

4. Feasibility of Gd-Based prostate cancer targeted magnetic resonance agents using prostate specific membrane antigen;Biochemical and Biophysical Research Communications;2022-06

5. Effect of Structural Fine-Tuning on Chelate Stability and Liver Uptake of Anionic MRI Contrast Agents;Journal of Medicinal Chemistry;2022-04-14