A novel albumin-binding macrocyclic Gd-HPDO3A complex bearing a deoxycholic acid residue: the role of the hydration state, water exchange and local dynamics in the observed relaxivity-Reference-Cited by-同舟云学术

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A novel albumin-binding macrocyclic Gd-HPDO3A complex bearing a deoxycholic acid residue: the role of the hydration state, water exchange and local dynamics in the observed relaxivity

Published:2024 Issue: Volume: Page:
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Hasallari Ferdeze¹²,Carrera Carla¹^ORCID,Cavallari Eleonora¹,Gianolio Eliana¹^ORCID,Aime Silvio³

Affiliation:

1. Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Centre, University of Torino Via Nizza 52, 10126 Torino, Italy

2. DiSIT – Department of Science and Technological Innovation, Università del Piemonte Orientale “A. Avogadro”, Viale T. Michel 11, 15121, Alessandria, Italy

3. IRCCS SDN SynLab, Via Gianturco 113, Naples, Italy

Abstract

Improved efficiency of an HSA-binding Gd-complex: the role of the hydration state, water exchange and local dynamics in the observed relaxivity of a highly stable macrocyclic Gd-HPDO3A complex bearing a deoxycholic acid residue.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QI/D4QI00894D

Reference55 articles.

1. Update on Gadolinium Based Contrast Agent Safety, From the AJR Special Series on Contrast Media

2. Ten years of gadolinium retention and deposition: ESMRMB-GREC looks backward and forward

3. Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review

4. How the Chemical Properties of GBCAs Influence Their Safety Profiles In Vivo

5. Gadolinium Deposition in the Brain: Current Updates

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