Palladium-catalyzed direct C–H arylation of 3-aryl-2H-benzo[1,2,4]thiadiazine 1,1-dioxides: an efficient strategy to the synthesis of benzothiadiazine-1,1-dioxide derivatives-Reference-Cited by-同舟云学术

Palladium-catalyzed direct C–H arylation of 3-aryl-2H-benzo[1,2,4]thiadiazine 1,1-dioxides: an efficient strategy to the synthesis of benzothiadiazine-1,1-dioxide derivatives

Published:2016 Issue:6 Volume:14 Page:1921-1924
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Dongyin¹²³⁴⁵,Liu Wei¹²³⁴⁵,Yi Fei¹²³⁴,Zhao Yongli¹²³⁴,Chen Junmin¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Jiangxi Normal University

3. Nanchang

4. PR China

5. Key Laboratory of Functional Small Organic Molecule

Abstract

An efficient strategy to the synthesis of 3-aryl-2H-benzo[1,2,4]thiadiazine 1,1-dioxide derivatives via palladium-catalyzed direct arylation of benzothiadiazine-1,1-dioxides with various aryl iodides is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02196K

Reference59 articles.

1. KATP channel openers: Structure-activity relationships and therapeutic potential

2. Toward Tissue-Selective Pancreatic B-Cells KATP Channel Openers Belonging to 3-Alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-Dioxides

3. Effect on KATP Channel Activation Properties and Tissue Selectivity of the Nature of the Substituent in the 7- and the 3-Position of 4H-1,2,4-Benzothiadiazine 1,1-Dioxides

4. 3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-Dioxides as ATP-Sensitive Potassium Channel Openers: Effect of 6,7-Disubstitution on Potency and Tissue Selectivity

5. Synthesis of Modified 4H-1,2,4-Benzothiadiazine-1,1-dioxides and Determination of their Affinity and Selectivity for Different Types of KATPChannels

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cascade [4 + 1] Annulation through Activation of the C(sp²)–H Bond Enabling Benzothiadiazinoisoindolcarboxylate, Benzothiadiazinoisoindole, and Benzothiadiazinoisoindolepyrrolidinedione as Hybrid Spiro-Heterocyclic Frameworks;The Journal of Organic Chemistry;2024-05-17

2. Rh(III)‐Catalyzed C−H Annulation of 3‐Aryl‐2H‐benzo[e][1,2,4]thiadiazine‐1,1‐dioxides with Vinylene Carbonates;European Journal of Organic Chemistry;2023-12-19

3. Derivation of Benzothiadiazine‐1,1‐dioxide Scaffolds via Transition Metal‐Catalyzed C—H Activation/Annulation;Chinese Journal of Chemistry;2023-05-09

4. Study the pharmacological potential of 1,2,4-thiadiazine 1,1-dioxides: A minireview;Al Mustansiriyah Journal of Pharmaceutical Sciences;2023-01-15

5. Rhodium-Catalyzed Annulations and Heck Coupling/Aza-Michael Addition for the Synthesis of Benzothiadiazinoisoquinoline 6,6-Dioxides and Benzothiadiazinoisoindole 5,5-Dioxides, Respectively;The Journal of Organic Chemistry;2022-09-01