A ribose modification of Spinach aptamer accelerates lead(ii) cation association in vitro-Reference-Cited by-同舟云学术

A ribose modification of Spinach aptamer accelerates lead(ii) cation association in vitro

Published:2019 Issue:42 Volume:55 Page:5882-5885
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Savage Jonathan C.¹²³⁴⁵,Shinde Pushkar¹²³⁴⁵,Bächinger Hans Peter¹²³⁴⁵,Davare Monika A.⁶⁷⁸⁴⁵,Shinde Ujwal¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biochemistry & Molecular Biology

2. Oregon Health & Science University

3. 3181 SW Sam Jackson Park Rd

4. Portland

5. USA

6. Papé Pediatric Research Institute

7. Division of Pediatric Hematology/Oncology, Department of Pediatrics

8. Oregon Health & Sciences University

Abstract

A 2′F ribose modification of pyrimidine residues in Spinach aptamer produces a construct with increased RNA chemical stability, but reduced structural stability of the G-quadruplex, resulting in accelerated association kinetics with model cation Pb²⁺.

Funder

National Institutes of Health

St. Baldrick's Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC01697J

Reference44 articles.

1. Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

2. A G-quadruplex–containing RNA activates fluorescence in a GFP-like fluorophore

3. RNA Mimics of Green Fluorescent Protein

4. In vitro selection of RNA molecules that bind specific ligands

5. Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Fluorogenic RNA-Based Biosensors of Small Molecules: Current Developments, Uses, and Perspectives;Biosensors;2024-08-01

2. Recent Development of Fluorescent Light-Up RNA Aptamers;Critical Reviews in Analytical Chemistry;2021-04-18

3. A Broccoli aptamer chimera yields a fluorescent K+ sensor spanning physiological concentrations;Chemical Communications;2021

4. Subtle sequence variations alter tripartite complex kinetics and G-quadruplex dynamics in RNA aptamer Broccoli;Chemical Communications;2020

5. Development and Applications of Fluorogen/Light-Up RNA Aptamer Pairs for RNA Detection and More;Methods in Molecular Biology;2020