Conformational stabilization of isatin Schiff bases – biologically active chemical probes-Reference-Cited by-同舟云学术

Conformational stabilization of isatin Schiff bases – biologically active chemical probes

Published:2017 Issue:17 Volume:7 Page:10070-10073
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Smirnov Andrey S.¹²³⁴²,Nikolaev Dmitriy N.⁵²³^ORCID,Gurzhiy Vlad V.⁴²³,Smirnov Sergey N.⁴²³,Suslonov Vitaliy S.⁴²³^ORCID,Garabadzhiu Alexander V.¹²³,Davidovich Pavel B.¹²³^ORCID

Affiliation:

1. Saint-Petersburg Technological Institute

2. St. Petersburg

3. Russia

4. Saint-Petersburg State University

5. Research Institute of Experimental Medicine

Abstract

Two ways of conformation stabilization for isatin Schiff bases (group of biologically active compounds) are reported here: complexation with metals that stabilize E-conformer and substitution in the 4^th position of isatin core stabilizing Z-form.

Funder

Ministry of Education and Science of the Russian Federation

Russian Foundation for Basic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA26779C

Reference20 articles.

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2. Diastereoselective Construction of 3-Aminooxindoles with Adjacent Stereocenters: Stereocontrolled Addition of γ-Substituted Allylindiums to Isatin Ketimines

3. Enzymatic Detection and Quantification Assay of Isatin, a Putative Stress Biomarker in Blood

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