Direct C3-arylations of 2-indolylmethanols with tryptamines and tryptophols via an umpolung strategy-Reference-Cited by-同舟云学术

Direct C3-arylations of 2-indolylmethanols with tryptamines and tryptophols via an umpolung strategy

Published:2018 Issue:9 Volume:16 Page:1536-1542
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wan Ying¹²³⁴,Wang Hai-Qing¹²³⁴,Xu Meng-Meng¹²³⁴,Mei Guang-Jian¹²³⁴,Shi Feng¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Materials Science

2. Jiangsu Normal University

3. Xuzhou

4. China

Abstract

A Brønsted acid-catalyzed direct C3-arylation of 2-indolylmethanols with tryptamines and tryptophols has been established, leading to a series of potentially bioactive 2,3′-biindole derivatives with a broad substrate scope and generally good yields (38 examples, up to 96% yield).

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Jiangsu Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB03182C

Reference81 articles.

1. Synthetic indole, carbazole, biindole and indolocarbazole-based receptors: applications in anion complexation and sensing