Synthesis and Antiproliferative Activity of 7-Azaindirubin-3′-oxime, a 7-Aza Isostere of the Natural Indirubin Pharmacophore-Reference-Cited by-同舟云学术

Synthesis and Antiproliferative Activity of 7-Azaindirubin-3′-oxime, a 7-Aza Isostere of the Natural Indirubin Pharmacophore

Published:2009-12-08 Issue:12 Volume:72 Page:2199-2202
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Kritsanida Marina¹,Magiatis Prokopios¹,Skaltsounis Alexios-Leandros¹,Peng Youyi¹,Li Peng¹,Wennogle Lawrence P.¹

Affiliation:

1. Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece, and Intra-Cellular Therapies Inc., 3960 Broadway, New York, New York 10032

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np9003905

Reference25 articles.

1. Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

2. GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

3. Tyrian Purple: 6,6’-Dibromoindigo and Related Compounds

4. Generation of New Protein Kinase Inhibitors Utilizing Cytochrome P450 Mutant Enzymes for Indigoid Synthesis

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