Selection of LNA-containing DNA aptamers against recombinant human CD73-Reference-Cited by-同舟云学术

Selection of LNA-containing DNA aptamers against recombinant human CD73

Published:2015 Issue:5 Volume:11 Page:1260-1270
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Elle Ida C.¹²³⁴⁵,Karlsen Kasper K.¹²³⁴⁵,Terp Mikkel G.⁶⁴⁷⁸,Larsen Niels⁹¹⁰⁸,Nielsen Ronni¹¹⁴⁵⁸,Derbyshire Nicola¹²³⁴⁵,Mandrup Susanne¹¹⁴⁵⁸,Ditzel Henrik J.⁶⁴⁷⁸¹²,Wengel Jesper¹²³⁴⁵

Affiliation:

1. Nucleic Acid Center

2. Department of Physics

3. Chemistry and Pharmacy

4. University of Southern Denmark

5. 5230 Odense M

6. Institute of Molecular Medicine

7. 5000 Odense C

8. Denmark

9. Danish Genome Institute

10. 8000 Aarhus C

11. Department of Biochemistry and Molecular Biology

12. Department of Oncology

Abstract

Aptamers containing LNA nucleotides were selected against recombinant human CD73 using SELEX and next generation sequencing (NGS) with custom NGS bioinformatics software (BION-apta).

Funder

European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MB/C5MB00045A

Reference46 articles.

1. The Chemical Biology of Aptamers

2. Aptamers as therapeutics

3. Therapeutic Applications of DNA and RNA Aptamers