Copper-catalyzed aerobic cyclizations of tetrahydroisoquinolines with bromoketones and alkenes for the synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines

Author:

Wang Wenhui1234ORCID,Sun Jinwei56789ORCID,Hu Huayou101112134ORCID,Liu Yun1234ORCID

Affiliation:

1. Jiangsu Key Laboratory of Green Synthesis for Functional Materials and School of Chemistry and Materials Science

2. Jiangsu Normal University

3. Xuzhou 221116

4. P. R. China

5. Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology

6. Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control

7. School of Environmental Science and Engineering

8. Nanjing University of Information Science & Technology

9. Nanjing 210044

10. Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials

11. School of Chemistry and Chemical Engineering

12. Huaiyin Normal University

13. Huaian 223300

Abstract

5,6-Dihydropyrrolo[1,2-a]isoquinolines have been synthesized via copper-catalyzed three-component aerobic cyclization reaction.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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