Three-component synthesis of new C<sup>3</sup>-substituted 5,6-dihydropyrrolo[2,1-<i>a</i>]isoquinolines

Author:

Miftyakhova A. R.1,Sidakov M. B.1,Borisova T. N.1,Fakhrutdinov A. N.2,Titov A. A.1,Sorokina E. A.1,Varlamov A. V.1

Affiliation:

1. Peoples’ Friendship University of Russia (RUDN University)

2. N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Abstract

New C3-substituted 5,6-dihydropyrrolo[2,1- a ]isoquinolines were obtained by a three-component domino reaction of 1-aroyl-3,4-dihydroisoquinolines, dimethylacetylenedicarboxylate, and CH-acids. The transformations proceed under microwave irradiation at 130°C in dry acetonitrile.

Publisher

The Russian Academy of Sciences

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